mavorixafor will raise the stage or impact of codeine by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a robust CYP2D6 inhibitor) is contraindicated with medicine which are really dependent on CYP2D6 for clearance.Sildenafil citrate is really a form of drug referred to as a PDE5 inhibitor, which just implies that it stop